MicrobeMS - A Matlab Toolbox for Microbial Identification Based on Mass Spectrometry

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The MicrobeMS software package is a program specifically designed for the analysis of MALDI-TOF mass spectra of microbial samples. The MicrobeMS software was developed by Peter Lasch at the Robert-Koch-Institute (RKI) in Berlin/Germany and can be used to identify microbial strains and species based on their mass spectral patterns. The program is a comprehensive Matlab-based package that operates under Windows 7/8/8.1/10/11 and LINUX (Debian, MicrobeMS versions later than 0.81). Original MALDI-TOF mass spectra in the format defined by Bruker Daltonics or by Shimadzu (via the mzXML data format) can be imported, processed and converted into a Matlab data matrix format specific to the MicrobeMS program.

The software allows standard mass spectrometry manipulations such as smoothing, baseline correction, normalization, peak detection, auto-calibration and some other functions. Since the software also runs in a full Windows or LINUX 64-bit environment, the number of spectra in the data sets is limited only by the amount of available memory (RAM).

Getting Started

Preparing Mass Spectra

Description of the Data File Formats

Import and Export of Mass Spectra and Mass Spectral Libraries

Spectral Analysis and Visualization

Identification and Classification

Identification of MS Biomarker Peaks